LRP-5, Human (Biotinylated, HEK293, His-Avi)

The LRP-5 protein functions as a coreceptor, cooperating with Frizzled receptors to initiate the canonical Wnt signaling pathway. It is critical for cell fate determination and self-renewal and plays an important role in posterior ectoderm patterning during gastrulation and bone development by affecting osteoblast proliferation and differentiation. LRP-5 Protein, Human (Biotinylated, HEK293, His-Avi) is the recombinant human-derived LRP-5 protein, expressed by HEK293 , with C-Avi, C-His labeled tag. The total length of LRP-5 Protein, Human (Biotinylated, HEK293, His-Avi) is 620 a.a., with molecular weight of 70-90 kDa.