MEK2, Human (Active, sf9, GST)

The MEK2 protein phosphorylates threonine and tyrosine residues in a Thr-Glu-Tyr sequence of MAP kinases. It activates ERK1 and ERK2 MAP kinases and BRAF through a KSR1 or KSR2-dependent mechanism. By binding to KSR1 or KSR2, it enables dimerization and activation of BRAF by releasing inhibitory intramolecular interactions (PubMed:29433126) . MEK2 Protein, Human (sf9, GST) is the recombinant human-derived MEK2 protein, expressed by Sf9 insect cells , with N-GST labeled tag.