TetR, E.coli (His-SUMO)

TetR protein acts as a repressor of the tetracycline resistance element and utilizes the helix-turn-helix structure of its N-terminal region for DNA binding. Tetracycline binding induces a conformational change in TetR that reduces its affinity to the tetA promoter operator site. TetR Protein, E.coli (His-SUMO) is the recombinant E. coli-derived TetR protein, expressed by E. coli , with N-SUMO, N-6*His labeled tag.