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FEN1-IN-2

FEN1-IN-2 (compound 20) is a flap endonuclease 1 (FEN1) inhibitor, with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively[1].

Product Specifications

CAS Number

824983-94-0

UNSPSC

12352005

Target

FLAP

Type

Reference compound

Related Pathways

Immunology/Inflammation

Applications

Cancer-programmed cell death

Field of Research

Cancer

Assay Protocol

https://www.medchemexpress.com/fen1-in-2.html

Purity

99.94

Solubility

DMSO : 90 mg/mL (ultrasonic)

Smiles

O=C(C1=CC=C(C2=CC(CN3C(N(C(C4=C3C=CS4)=O)O)=O)=CC=C2)C=C1)N

Molecular Formula

C20H15N3O4S

Molecular Weight

393.42

References & Citations

[1]L Nathan Tumey, et al. The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors. Bioorg Med Chem Lett. 2005 Jan 17;15 (2) :277-81.

Shipping Conditions

Room Temperature

Storage Conditions

-20°C, 3 years; 4°C, 2 years (Powder)

Scientific Category

Reference compound1

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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