FEN1-IN-2
FEN1-IN-2 (compound 20) is a flap endonuclease 1 (FEN1) inhibitor, with IC50 values of 3 nM and 226 nM for FEN1 and XPG, respectively[1].
Product Specifications
CAS Number
824983-94-0
UNSPSC
12352005
Target
FLAP
Type
Reference compound
Related Pathways
Immunology/Inflammation
Applications
Cancer-programmed cell death
Field of Research
Cancer
Assay Protocol
https://www.medchemexpress.com/fen1-in-2.html
Purity
99.94
Solubility
DMSO : 90 mg/mL (ultrasonic)
Smiles
O=C(C1=CC=C(C2=CC(CN3C(N(C(C4=C3C=CS4)=O)O)=O)=CC=C2)C=C1)N
Molecular Formula
C20H15N3O4S
Molecular Weight
393.42
References & Citations
[1]L Nathan Tumey, et al. The identification and optimization of a N-hydroxy urea series of flap endonuclease 1 inhibitors. Bioorg Med Chem Lett. 2005 Jan 17;15 (2) :277-81.
Shipping Conditions
Room Temperature
Storage Conditions
-20°C, 3 years; 4°C, 2 years (Powder)
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Available Sizes
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