MAdCAM1, Human (299a.a, HEK293, His)

MAdCAM1 is a cell adhesion leukocyte receptor expressed primarily by mucosal venules and plays a critical role in coordinating lymphocyte trafficking into mucosal tissues, particularly Peyer's patches and intestinal lamina propria. This protein exhibits the ability to bind integrins α-4/β-7 and L-selectin, thereby regulating the passage and retention of leukocytes in the mucosal environment. MAdCAM1 Protein, Human (299a.a, HEK293, His) is the recombinant human-derived MAdCAM1 protein, expressed by HEK293, with C-His labeled tag.