GFRAL, Mouse (HEK293, His)
GFRAL protein, a brainstem-restricted receptor, regulates food intake, energy expenditure, and body weight in response to metabolic and toxin-induced stresses. It binds with GDF15, interacts with RET, and activates MAPK- and AKT- signaling pathways. GFRAL acts as a receptor for GDF15 and mediates cellular signaling through RET, requiring prior GDF15 binding. GFRAL Protein, Mouse (HEK293, His) is the recombinant mouse-derived GFRAL protein, expressed by HEK293, with C-His labeled tag.
Product Specifications
Product Name Alternative
GFRAL Protein, Mouse (HEK293, His), Mouse, HEK293
UNSPSC
12352202
Molecular Formula
404194 (Gene_ID) Q6SJE0-1 (Q20-G349) (Accession)
Molecular Weight
Approximately 45-55 kDa, based on SDS-PAGE under reducing conditions, due to the glycosylation.
Shipping Conditions
Room temperature in continental US; may vary elsewhere.
Scientific Category
Recombinant Proteins
Frequently Asked Questions
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