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IL-5, Human (HEK293)

The IL-5 Protein, predominantly expressed by T-lymphocytes and NK cells, is crucial for eosinophil survival, differentiation, and chemotaxis. It also affects B-cells, inducing immunoglobulin production, growth, and differentiation. IL-5 Protein activates kinases like LYN, SYK, and JAK2, which signal through RAS-MAPK and JAK-STAT5 pathways. It exists as a disulfide-linked homodimer and interacts with IL5RA and CSF2RB subunits. IL-5 Protein, Human (HEK293) is the recombinant human-derived IL-5 protein, expressed by HEK293, with tag free.

Product Specifications

Product Name Alternative

IL-5 Protein, Human (HEK293), Human, HEK293

UNSPSC

12352202

Molecular Formula

3567 (Gene_ID) P05113-1 (I20-S134) (Accession)

Molecular Weight

Approximately 15-21 kDa, based on SDS-PAGE under reducing conditions,36 kDa, based on SDS-PAGE under non-reduced conditions, due to the glycosylation.

Shipping Conditions

Room temperature in continental US; may vary elsewhere.

Scientific Category

Recombinant Proteins

Frequently Asked Questions

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