Met-12

Met-12 is a small peptide inhibitor of the Fas receptor. Met-12 can inhibit Fas receptor-mediated photoreceptor cell apoptosis, reduce Caspase activation. Met-12 can be used in the research of photoreceptor[1].

Product Specifications

CAS Number

[1242964-46-0]

UNSPSC

12352209

Target

Apoptosis; Caspase

Related Pathways

Apoptosis

Field of Research

Others

Purity

99.66

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](C)NC(CNC([C@H](CC(C)C)NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@@H](N)CC2=CN=CN2)=O)CC3=CN=CN3)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC5=CC=C(C=C5)O)=O)=O

Molecular Formula

C71H99N17O17

Molecular Weight

1462.65

References & Citations

[1]Besirli CG, et al. Inhibition of retinal detachment-induced apoptosis in photoreceptors by a small peptide inhibitor of the fas receptor. Invest Ophthalmol Vis Sci. 2010 Apr;51 (4) :2177-84.