Met-12
Met-12 is a small peptide inhibitor of the Fas receptor. Met-12 can inhibit Fas receptor-mediated photoreceptor cell apoptosis, reduce Caspase activation. Met-12 can be used in the research of photoreceptor[1].
Product Specifications
CAS Number
[1242964-46-0]
UNSPSC
12352209
Target
Apoptosis; Caspase
Related Pathways
Apoptosis
Field of Research
Others
Purity
99.66
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
OC(C=C1)=CC=C1C[C@H](NC([C@H](CC(N)=O)NC([C@H](C(C)C)NC([C@H](C)NC(CNC([C@H](CC(C)C)NC([C@@H](NC([C@H]([C@@H](C)CC)NC([C@@H](NC([C@@H](N)CC2=CN=CN2)=O)CC3=CN=CN3)=O)=O)CC4=CC=C(C=C4)O)=O)=O)=O)=O)=O)=O)C(N[C@@H]([C@@H](C)CC)C(N[C@H](C(O)=O)CC5=CC=C(C=C5)O)=O)=O
Molecular Formula
C71H99N17O17
Molecular Weight
1462.65
References & Citations
[1]Besirli CG, et al. Inhibition of retinal detachment-induced apoptosis in photoreceptors by a small peptide inhibitor of the fas receptor. Invest Ophthalmol Vis Sci. 2010 Apr;51 (4) :2177-84.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Curated Selection
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