KLA peptide (acetate)

KLA peptide acetate a cationic amphipathic mitochondrial membrane disrupting peptide that induces cell apoptosis by disrupting mitochondrial membrane. KLA peptide acetate can be used for the researches of cancer, inflammation, and neurological disease[1][2].

Product Specifications

UNSPSC

12352209

Target

Apoptosis

Related Pathways

Apoptosis

Applications

COVID-19-immunoregulation

Field of Research

Cancer; Inflammation/Immunology; Neurological Disease

Purity

99.81

Solubility

H2O : ≥ 100 mg/mL

Smiles

O=C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCCCN)N.CC(O)=O.[x]

Molecular Formula

C72H138N20O15.xC2H4O2

Molecular Weight

1523.99 (free base)

References & Citations

[1]Guo Z, et al. Specific hepatic stellate cell-penetrating peptide targeted delivery of a KLA peptide reduces collagen accumulation by inducing apoptosis. J Drug Target. 2017 Sep;25 (8) :715-723.|[2]Zen R, et al. Pro-inflammatory microglia-targeted peptide therapy ameliorates neonatal hypoxic-ischemic encephalopathy in mice. Mol Ther. 2025 Jul 2;33 (7) :3177-3194.