Palmitoyl tetrapeptide-10

Palmitoyl tetrapeptide-10 is a bioactive peptide. Palmitoyl tetrapeptide-10 works synergistically with other active ingredients to increase the expression of corneodesmosin (a marker of keratinocyte adhesion) and filaggrin (a marker of keratinocyte terminal differentiation), thereby reducing skin permeability and improving skin barrier function. Palmitoyl tetrapeptide-10 can be used in the research of sensitive skin syndrome and skin pigmentation[1][2].

Product Specifications

CAS Number

[887140-79-6]

UNSPSC

12352209

Target

Others

Related Pathways

Others

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Endocrinology; Metabolic Disease

Purity

99.46

Solubility

10 mM in DMSO

Smiles

O=C(N[C@@H]([C@H](O)C)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCCN)C(O)=O)=O)=O)[C@H](CCCCN)NC(CCCCCCCCCCCCCCC)=O

Molecular Formula

C41H72N6O7

Molecular Weight

761.05

References & Citations

[1]Wenner K, et al. An Open-Label Study Assessing the Efficacy and Tolerability of a Skincare Regimen in Subjects of Different Ethnicities with Moderate-to-Severe Hyperpigmentation. J Cosmet Dermatol. 2022;21 (6) :2497-2507.|[2]Polena H, et al. Evaluation of the sensitive skin syndrome and the effect of a dermo-cosmetic treatment in Thai and Polish subjects. Int J Cosmet Sci. 2025 Aug 19.