Palmitoyl tetrapeptide-20
Palmitoyl tetrapeptide-20 (PTP20) is a biomimetic peptide agonist of α-MSH. Palmitoyl tetrapeptide-20 promotes hair pigmentation and delays hair graying by activating the MC1-R pathway (AC50: 0.16 nM), enhancing catalase activity to reduce H2O2 accumulation, and upregulating SIRT1 activity. Palmitoyl tetrapeptide-20 can be used in research on preventing hair loss and improving hair graying[1].
Product Specifications
Product Name Alternative
PTP20
UNSPSC
12352209
Target
Melanocortin Receptor; Sirtuin
Related Pathways
Cell Cycle/DNA Damage; Epigenetics; GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease; Inflammation/Immunology
Purity
99.67
Solubility
DMSO : 28.57 mg/mL (adjust pH to 4 with 1 M HCl)
Smiles
CCCCCCCCCCCCCCCC(N1[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(O)=O)CCCCN)=O)CCCCN)=O)CCC(O)=O)=O)CCC1)=O
Molecular Formula
C38H70N6O8
Molecular Weight
739.00
References & Citations
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
MC1R; SIRT1
Available Sizes
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