[Dmt1]DALDA

[Dmt1]DALDA is a potent and long-acting analgesic binds to the mu opioid receptor with high affinity and selectivity. [Dmt1]DALDA is a full agonist at hMOR (Kd = 0.199 nM) and hDOR, but only partial agonist against hKOR[1][2].

Product Specifications

CAS Number

[255861-98-4]

UNSPSC

12352209

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Others

Smiles

CC(C=C(C=C1C)O)=C1C[C@H](N)C(N[C@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CC2=CC=CC=C2)=O)=O

Molecular Formula

C32H49N9O5

Molecular Weight

639.79

References & Citations

[1]Zhao, G. M., et al., (2003) . Comparison of [Dmt1]DALDA and DAMGO in binding and G protein activation at mu, delta, and kappa opioid receptors. The Journal of pharmacology and experimental therapeutics, 307 (3), 947–954.