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Tetraproline

Tetraproline is a fragment sequence in tristetraprolin (TTP) . Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements[1].

Product Specifications

CAS Number

[21866-90-0]

UNSPSC

12352209

Target

Others

Related Pathways

Others

Field of Research

Others

Solubility

10 mM in DMSO

Smiles

O=C([C@H]1N(CCC1)C([C@@H]2CCCN2)=O)N3[C@@H](CCC3)C(N4[C@@H](CCC4)C(O)=O)=O

Molecular Formula

C20H30N4O5

Molecular Weight

406.48

References & Citations

[1]Fu R, et, al. Recruitment of the 4EHP-GYF2 cap-binding complex to tetraproline motifs of tristetraprolin promotes repression and degradation of mRNAs with AU-rich elements. RNA. 2016 Mar;22 (3) :373-82.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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