CIGB-300 (acetate)
CIGB-300 acetate (P15-Tat acetate) is an anti-casein kinase 2 (CK2) peptide that exhibits anticancer properties by interfering with the phosphorylation of protein kinase CK2. CIGB-300 acetate induces apoptosis in multiple tumor cell lines and can be used in cancer research[1].
Product Specifications
Product Name Alternative
P15-Tat (acetate)
UNSPSC
12352209
Target
Apoptosis; Casein Kinase
Related Pathways
Apoptosis; Cell Cycle/DNA Damage; Stem Cell/Wnt
Applications
Cancer-Kinase/protease
Field of Research
Cancer
Purity
98.00
Smiles
O=C1N[C@@H](CCSC)C(N[C@@H](CO)C(N2[C@]([H])(C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC3=CN=CN3)C(N[C@@H](CC(C)C)C(NCC(N[C@@]([H])([C@@H](C)O)C(N[C@H](C(O)=O)CSSC[C@H](NC(CCNC([C@@H](NC([C@H]4N(C([C@H]5N(C([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@@H](NC([C@H](CCCNC(N)=N)NC(CN)=O)=O)CCCCN)=O)CCCCN)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC(N)=O)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCCNC(N)=N)=O)CCC5)=O)CCC4)=O)CCC(N)=O)=O)=O)C(N[C@H]1CC6=CNC7=CC=CC=C67)=O)=O)=O)=O)=O)=O)=O)CCC2)=O)=O.CC(O)=O.[x]
Molecular Formula
C127H215N53O30S3.xC2H4O2
Molecular Weight
3060.60 (free base)
References & Citations
[1]Perea S E, et al. CIGB-300, a novel proapoptotic peptide that impairs the CK2 phosphorylation and exhibits anticancer properties both in vitro and in vivo[J]. Molecular and cellular biochemistry, 2008, 316: 163-167.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
Phase 2
Available Sizes
Frequently Asked Questions
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