TNO003 (TFA)
TNO003 TFA is a selective fluorogenic substrate for stromelysin-1 (MMP-3) . TNO003 TFA has higher selectivity for MMP-3 than MMP-1, MMP-2, MMP-7, MMP-8, MMP-9 and MMP-13. TNO003 TFA can be used for the determination of stromelysin activity (Ex/Em = 360/490 nm) [1].
Product Specifications
UNSPSC
12352211
Target
Fluorescent Dye; MMP
Related Pathways
Metabolic Enzyme/Protease; Others
Field of Research
Others
Smiles
FC(C(O)=O)(F)F.O=C([C@H]1N(CCC1)C([C@H](CCCCN)NC([C@H]2N(CCC2)C([C@H](CCCNC(N)=N)NC(CCCNC(C3=CC=C(C=C3)/N=N/C4=CC=C(C=C4)N(C)C)=O)=O)=O)=O)=O)N[C@@H](C(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@@H](C)C(N[C@H](C(N)=O)CCCCN)=O)=O)CCC(NCCNC7=CC=CC8=C7C=CC=C8S(=O)(O)=O)=O)=O)=O)=O)=O)=O
Molecular Formula
C101H145F3N28O22S
Molecular Weight
2192.47
References & Citations
[1]B Beekman, et al. Highly increased levels of active stromelysin in rheumatoid synovial fluid determined by a selective fluorogenic assay. FEBS Lett. 1997 Dec 1;418 (3) :305-9.
Shipping Conditions
Room temperature
Scientific Category
Reference compound1
Clinical Information
No Development Reported
Frequently Asked Questions
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