β-Amyloid (1-38) (TFA)
β-Amyloid (1-38) (Aβ (1-38) ) TFA is a β-Amyloid (Aβ) peptide. β-Amyloid (1-38) TFA interferes with the conversion of Aβ (1-42) to a β-sheet-rich aggregate. β-Amyloid (1-38) TFA reverses the negative impact of Aβ (1-42) on long-term potentiation in acute hippocampal slices and on membrane conductance in primary neurons, and mitigates an Aβ (1-42) phenotype in Caenorhabditis elegans[1].
Product Specifications
Product Name Alternative
Aβ (1-38) (TFA) ; Aβ38 (TFA)
UNSPSC
12352209
Target
Amyloid-β
Related Pathways
Neuronal Signaling
Field of Research
Neurological Disease
Purity
99.38
Solubility
DMSO : 50 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CNC=N2)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(NCC(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](CCC(O)=O)C(N[C@@H](C(C)C)C(N[C@@H](CC4=CNC=N4)C(N[C@@H](CC5=CNC=N5)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](C(C)C)C(N[C@@H](CC6=CC=CC=C6)C(N[C@@H](CC7=CC=CC=C7)C(N[C@@H](C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(O)=O)C(N[C@@H](C(C)C)C(NCC(N[C@@H](CO)C(N[C@@H](CC(N)=O)C(N[C@@H](CCCCN)C(NCC(N[C@@H](C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H]([C@@H](C)CC)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N[C@@H](C(C)C)C(NCC(NCC(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N.OC(C(F)(F)F)=O.[x]
Molecular Formula
C184H277N51O56S.xC2HF3O2
Molecular Weight
4131.54 (free base)
References & Citations
[1]Maa O Quartey, et al. The Aβ (1-38) peptide is a negative regulator of the Aβ (1-42) peptide implicated in Alzheimer disease progression. Sci Rep. 2021 Jan 11;11 (1) :431.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
