IDR-1018 (acetate)
IDR-1018 acetate is an innate defense regulator conjugate, with MICs of 16 μg/mL for MRSA USA300 LAC, MRSA SAP 0017 and S. epidermidis ATCC14990. IDR-1018 acetate can be used to synthesis V-IDR1018 (vancomycin-innate defense regulator conjugate) [1][2].
Product Specifications
UNSPSC
12352209
Target
Antibiotic; Bacterial; Parasite
Related Pathways
Anti-infection
Applications
COVID-19-immunoregulation
Field of Research
Infection; Inflammation/Immunology
Purity
99.57
Solubility
H2O : 50 mg/mL (ultrasonic)
Smiles
O=C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC(C)C)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](C(C)C)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H]([C@@H](C)CC)C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C(C)C)N.CC(O)=O.[x]
Molecular Formula
C71H126N26O12.xC2H4O2
Molecular Weight
1535.93 (free base)
References & Citations
[1]Hashem Etayash, Multifunctional Antibiotic–Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response. J. Med. Chem. 2021, 64, 22, 16854-16863.|[2]Hashem Etayash, et al. Correction to “Multifunctional Antibiotic–Host Defense Peptide Conjugate Kills Bacteria, Eradicates Biofilms, and Modulates the Innate Immune Response”. J. Med. Chem. 2022, 65, 3, 2710-2711.|[3]François Niyonsaba, et al. The innate defense regulator peptides IDR-HH2, IDR-1002, and IDR-1018 modulate human neutrophil functions. J Leukoc Biol. 2013 Jul;94 (1) :159-70.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
M-CEM-NS-HGB-MPL-1Pi 1 Unit
Hybrid Grid Box; holds both clipped and unclipped grids
Sign In for Pricing
View Details E45M16657V-2 50 µL
Cardiac Troponin I (TNNC1) Mouse Monoclonal Antibody [Clone 1H5]
Sign In for Pricing
View Details