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Targeting the bacterial sliding clamp peptide 46 (TFA)

Targeting the bacterial sliding clamp peptide 46 TFA is a short peptide targeting the bacterial sliding clamp (SC), inhibiting SC-dependent DNA synthesis[1].

Product Specifications

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

99.83

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

OC(C(F)(F)F)=O.CC(C[C@@H](C(N1CCC[C@H]1C(N[C@H](C(O)=O)CC2=CC=CC=C2)=O)=O)NC([C@@H](N(C([C@@H](NC([C@@H](NC(/C=C/C3=CC=CN=C3)=O)CCC(N)=O)=O)CC4CCCCC4)=O)C)CC(O)=O)=O)C.[x]

Molecular Formula

C47H64N8O11.xC2HF3O2

Molecular Weight

917.06 (free base)

References & Citations

[1]Monsarrat C, et al. Iterative Structure-Based Optimization of Short Peptides Targeting the Bacterial Sliding Clamp. J Med Chem. 2021 Nov 22.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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