JKC 302
JKC 302 is an ET-A receptor antagonist. JKC 302 partly blocks ET-1-induced contraction in asthmatic rat trachea ring[1][2].
Product Specifications
CAS Number
[153982-38-8]
UNSPSC
12352209
Target
Endothelin Receptor
Related Pathways
GPCR/G Protein
Field of Research
Cardiovascular Disease
Smiles
O=C(N[C@@H](C(N1[C@](CCC1)([H])C(N[C@@H](C(N[C@H](C(N2)=O)CC(C)C)=O)C(C)C)=O)=O)CO)[C@H]2CC3=CNC4=CC=CC=C34
Molecular Formula
C30H42N6O6
Molecular Weight
582.69
References & Citations
[1]Basilico N, et al. The lipid moiety of haemozoin (Malaria Pigment) and P. falciparum parasitised red blood cells bind synthetic and native endothelin-1. J Biomed Biotechnol. 2010;2010:854927.|[2]Tiequn HUANG, et al. Role of endothelin and nitric oxide in the pathogenesis of asthma. Chinese Journal of Pathophysiology ; (12) : 435-437, 2001.
Shipping Conditions
Room temperature
Product MSDS
http://file.medchemexpress.com/batch_PDF/HY-P3228/
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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