Tozuleristide

Tozuleristide is a tumor-targeting agent covalently conjugated to a derivative of the near-infrared fluorescent dye indocyanine green (ICG) . Tozuleristide has the ability to penetrate the blood-brain barrier. Tozuleristide can be used in research related to fluorescence-guided surgery (FGS) [1].

Product Specifications

CAS Number

1673565-40-6

UNSPSC

12352209

Target

Others

Related Pathways

Others

Field of Research

Cancer

Smiles

[H]N[C@H](C(N[C@H](C(N[C@H](C(N1CCC[C@H]1C(N[C@H](C(N[C@H](C(N[C@]([C@H](O)C)([H])C(N[C@]([C@H](O)C)([H])C(N[C@H](C(N[C@H](C(N[C@@H](CCC(N)=O)C(N[C@H](C(N[C@H](C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N[C@H](C(N[C@H](C(N2)=O)CC(O)=O)=O)CC(O)=O)=O)CSSC[C@H]3C(N[C@@H](CC(C)C)C(N4)=O)=O)=O)=O)=O)C)=O)CCSC)=O)=O)CC5=CN=CN5)=O)CC(O)=O)=O)=O)=O)CC6=CC=CC=C6)=O)CSSC[C@H]7C(N[C@H](C(NCC(N8CCC[C@H]8C(N[C@@H](CCC(N)=O)C(N3)=O)=O)=O)=O)CC(C=C9)=CC=C9O)=O)=O)=O)CCSC)=O)CSSC[C@H]2C(N[C@H](C(NCC(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CCCCN)C(N7)=O)=O)=O)=O)=O)=O)=O)=O)CSSC[C@H]4C(N[C@@H](CCCNC(N)=N)C(O)=O)=O)=O)=O)CCSC

Molecular Formula

C158H248N56O48S11

Molecular Weight

4052.72

References & Citations

[1]Kobets AJ, et al. Unexpected Binding of Tozuleristide "Tumor Paint" to Cerebral Vascular Malformations: A Potentially Novel Application of Fluorescence-Guided Surgery. Neurosurgery. 2021 Jul 15;89 (2) :204-211.