CPN-267 (TFA)

CPN-267 (compound 7b) TFA is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC50 of 0.25 nM. CPN-267 TFA suppresses body weight gain in mice and can be used for study of obesity[1].

Product Specifications

UNSPSC

12352209

Target

Neuromedin U Receptor (NMUR)

Related Pathways

GPCR/G Protein

Applications

Metabolism-protein/nucleotide metabolism

Field of Research

Metabolic Disease

Purity

99.20

Smiles

O=C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC(N)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CC2=CNC3=CC=CC=C23)NC([C@](NC(CC4=CC=CS4)=O)(C)CC5=CNC6=CC=CC=C56)=O)=O.O=C(C(F)(F)F)O.O=C(C(F)(F)F)O

Molecular Formula

C54H68F6N16O12S

Molecular Weight

1279.27

References & Citations

[1]Takayama K, et al. Discovery of a Human Neuromedin U Receptor 1-Selective Hexapeptide Agonist with Enhanced Serum Stability [published correction appears in J Med Chem. 2017 Sep 14;60 (17) :7613.