CPN-267 (TFA)
CPN-267 (compound 7b) TFA is a selective neuromedin U receptor 1 (NMUR1) agonist with the EC50 of 0.25 nM. CPN-267 TFA suppresses body weight gain in mice and can be used for study of obesity[1].
Product Specifications
UNSPSC
12352209
Target
Neuromedin U Receptor (NMUR)
Related Pathways
GPCR/G Protein
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Purity
99.20
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CCCNC(N)=N)C(N[C@H](C(N)=O)CC(N)=O)=O)=O)[C@H](CCCNC(N)=N)NC([C@H](CC2=CNC3=CC=CC=C23)NC([C@](NC(CC4=CC=CS4)=O)(C)CC5=CNC6=CC=CC=C56)=O)=O.O=C(C(F)(F)F)O.O=C(C(F)(F)F)O
Molecular Formula
C54H68F6N16O12S
Molecular Weight
1279.27
References & Citations
[1]Takayama K, et al. Discovery of a Human Neuromedin U Receptor 1-Selective Hexapeptide Agonist with Enhanced Serum Stability [published correction appears in J Med Chem. 2017 Sep 14;60 (17) :7613.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
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