Isocitrate dehydrogenase, Microorganism

Isocitrate dehydrogenase, Microorganism (IDH) (EC 1.1.1.42) is a citric acid or tricarboxylic acid cycle enzyme, is often used in biochemical studies. Isocitrate dehydrogenase catalyzes the oxidative decarboxylation of isocitrate to α-ketoglutarate and reduces NAD (P) + to NAD (P) H, it plays important roles in cellular metabolism[1].

Product Specifications

CAS Number

[9028-48-2]

Product Name Alternative

ICDH, Microorganism; IDH, Microorganism

UNSPSC

12352204

Target

Isocitrate Dehydrogenase (IDH)

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Metabolic Disease

Smiles

[Isocitratedehydrogenase,Microorganism]

References & Citations

[1]Reitman ZJ, Yan H. Isocitrate dehydrogenase 1 and 2 mutations in cancer: alterations at a crossroads of cellular metabolism. J Natl Cancer Inst. 2010 Jul 7;102 (13) :932-41.