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PNGase F (Lyophilized)

PNGase F (Lyophilized) is a glycosidase expressed by recombinant E. coli. PNGase F (Lyophilized) can selectively hydrolyze all N-glycans linked to Asn in proteins except those containing α1-3 fucosidic bonds. The cleavage site is the glycosidic bond between Asn and the innermost GIcNAc, which releases sugar molecules linked to asparagine from glycoproteins and converts asparagine to aspartic acid. The cleaved glycoforms include high mannose, hybrid and complex oligosaccharides[1].

Product Specifications

CAS Number

[83534-39-8]

UNSPSC

12352204

Target

Glycosidase

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Cancer

Smiles

[PNGaseF(Lyophilized)]

References & Citations

[1]Vilaj M, et al. Evaluation of different PNGase F enzymes in immunoglobulin G and total plasma N-glycans analysis. Glycobiology. 2021 Jan 9;31 (1) :2-7.

Shipping Conditions

Blue Ice

Storage Conditions

Store at -20°C for 2 years

Scientific Category

Enzyme

Clinical Information

No Development Reported

Curated Selection

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