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Destruxin B2

Destruxin B2 (compound 5) is a natural depsipeptide that can be inhibits hepatitis B surface antigen (HBsAg) secretion in Hep3B cells with an IC50 1.30 μM[1].

Product Specifications

CAS Number

79386-00-8

UNSPSC

12352209

Target

HBV

Related Pathways

Anti-infection

Field of Research

Infection

Smiles

O=C1N2[C@](CCC2)([H])C(N[C@H](C(N([C@H](C(N([C@H](C(NCCC(O[C@@H]1CC(C)C)=O)=O)C)C)=O)C(C)C)C)=O)C(C)C)=O

Molecular Formula

C29H49N5O7

Molecular Weight

579.73

References & Citations

[1]Yeh SF, et al. Study of structure-activity correlation in destruxins, a class of cyclodepsipeptides possessing suppressive effect on the generation of hepatitis B virus surface antigen in human hepatoma cells. Biochem Biophys Res Commun. 1996 Dec 4;229 (1) :65-72.

Shipping Conditions

Room temperature

Scientific Category

Natural Products

Clinical Information

No Development Reported

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