BPP 5a
BPP 5a is a bradykinin-potentiating peptide with vasorelaxant activity, which is found in Bothrops jararaca venom. BPP 5a is an angiotensin-converting enzyme (ACE) inhibitor with a Ki value of 400 nM. BPP 5a is promising for research of hypertension and cardiovascular diseases[1].
Product Specifications
CAS Number
[30505-63-6]
UNSPSC
12352209
Target
Angiotensin Receptor; Peptide-Drug Conjugates (PDCs)
Related Pathways
Antibody-drug Conjugate/ADC Related; GPCR/G Protein
Applications
Neuroscience-Neuromodulation
Field of Research
Cardiovascular Disease
Smiles
O=C([C@H]1NC(CC1)=O)N[C@@H](CCCCN)C(N[C@H](C(N[C@@H](C)C(N2[C@@H](CCC2)C(O)=O)=O)=O)CC3=CNC4=CC=CC=C34)=O
Molecular Formula
C30H41N7O7
Molecular Weight
611.69
References & Citations
[1]Ianzer D, et al. BPP-5a produces a potent and long-lasting NO-dependent antihypertensive effect. Ther Adv Cardiovasc Dis. 2011 Dec;5 (6) :281-95.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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