BAD (103-127) (human), FAM-labeled (TFA)

BAD (103-127) (human), FAM-labeled TFA is a FAM-labeled human BAD (103-127) (HY-P2468) . BAD (103-127) (human) TFA, the 25-mer Bad peptide, is derived from the BH3 domain of BAD and can antagonize the function of Bcl-xL[1].

Product Specifications

UNSPSC

12352209

Target

Bcl-2 Family

Related Pathways

Apoptosis

Field of Research

Cancer

Purity

95.10

Smiles

OC1=CC2=C(C=C1)C3(C4=C(C=C(C=C4)C(N[C@@H](CC(N)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(N[C@@H](C)C(N[C@@H](C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC7=CC=C(C=C7)O)C(NCC(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(C)C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CCSC)C(N[C@@H](CO)C(N[C@@H](CC(O)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC8=CC=CC=C8)C(N[C@@H](C(C)C)C(N[C@@H](CC(O)=O)C(N[C@@H](CO)C(N[C@@H](CC9=CC=CC=C9)C(N[C@@H](CCCCN)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)C(O3)=O)C%10=C(C=C(C=C%10)O)O2.O=C(O)C(F)(F)F.[x]

Molecular Formula

C158H222N42O45S.xC2HF3O2

Molecular Weight

3461.77 (free base)

References & Citations

[1]Dilraj Lama, et al. Molecular dynamics simulations of pro-apoptotic BH3 peptide helices in aqueous medium: relationship between helix stability and their binding affinities to the anti-apoptotic protein Bcl-X (L) . J Comput Aided Mol Des. 2011 May;25 (5) :413-26.