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PD-149163

PD-149163 is an NTR-1 agonist. PD-149163 reverses intestinal damage through its anti-inflammatory, antioxidant, and cell proliferation promoting properties. PD-149163 has antipsychotic effects. PD-149163 is commonly used in research on mental illness and intestinal injury[1].

Product Specifications

CAS Number

169528-11-4

UNSPSC

12352209

Target

Neurotensin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Field of Research

Inflammation/Immunology; Neurological Disease

Smiles

CC(C)C[C@@H](C(OCC)=O)NC([C@H](C(C)(C)C)NC([C@H](CC1=CNC2=C1C=CC=C2)NC([C@H]3N(C([C@H](CCCCN)NC[C@@H](N)CCCCN)=O)CCC3)=O)=O)=O

Molecular Formula

C42H71N9O6

Molecular Weight

798.07

References & Citations

[1]Mishra A, et al. Protective effect of neurotensin receptor-1 agonist PD 149163 against lipopolysaccharide-induced gut toxicity in mice. Drug Chem Toxicol. 2022 Nov;45 (6) :2399-2410.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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