Z-LRGG-AMC (TFA)
Z-LRGG-AMC TFA is the trifluoroacetate salt of Z-LRGG-AMC (HY-P2176) . Z-LRGG-AMC TFA is a fluorogenic substrate for isopeptidase T. Upon cleavage of Z-LRGG-AMC TFA by isopeptidase T, 7-amino-4-methylcoumarin (AMC) is released, and its fluorescence can be used to quantify isopeptidase T activity (Ex/Em : 360/460 nm) [1].
Product Specifications
Product Name Alternative
Z-Leu-Arg-Gly-Gly-AMC (TFA)
UNSPSC
12352209
Target
Fluorescent Dye
Related Pathways
Others
Field of Research
Others
Smiles
CC(C1=CC=C(NC(CNC(CNC([C@H](CCCNC(N)=N)NC([C@H](CC(C)C)NC(OCC2=CC=CC=C2)=O)=O)=O)=O)=O)C=C1O3)=CC3=O.FC(C(O)=O)(F)F
Molecular Formula
C36H45F3N8O10
Molecular Weight
806.79
References & Citations
[1]Stein RL, et al. Kinetic studies of isopeptidase T: modulation of peptidase activity by ubiquitin. Biochemistry. 1995 Oct 3;34 (39) :12616-23.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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