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Maraciclatide

Maraciclatide is a synthetic molecule that binds with high affinity to αvβ3 and αvβ5 integrins via the RGD peptide. Maraciclatide can be used to detect bone metastasis, breast tumors, vascular disease and rheumatoid arthritis in animal models. Maraciclatide can be studied in research on angiogenesis and inflammation[1].

Product Specifications

CAS Number

[489427-17-0]

UNSPSC

12352209

Target

Integrin

Related Pathways

Cytoskeleton

Field of Research

Cancer; Inflammation/Immunology

Smiles

C/C(C(NCCC(CCNC(CCCC(NCCCC[C@H]1C(N[C@H]2CSSC[C@H](C(N[C@H](C(N[C@@H](CSCC(N1)=O)C(NCCOCCOCCOCCNC(COCC(N)=O)=O)=O)=O)CC3=CC=CC=C3)=O)NC([C@@H](NC(CNC([C@@H](NC2=O)CCCNC(N)=N)=O)=O)CC(O)=O)=O)=O)=O)=O)CCNC(/C(C)=N/O)(C)C)(C)C)=N\O

Molecular Formula

C72H120N20O21S3

Molecular Weight

1698.04

References & Citations

[1]Gibbons, T., et al., (2024) . Safety, biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 99m Tc-maraciclatide in healthy volunteers. Nuclear medicine communications, 45 (4), 295-303

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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