Maraciclatide
Maraciclatide is a synthetic molecule that binds with high affinity to αvβ3 and αvβ5 integrins via the RGD peptide. Maraciclatide can be used to detect bone metastasis, breast tumors, vascular disease and rheumatoid arthritis in animal models. Maraciclatide can be studied in research on angiogenesis and inflammation[1].
Product Specifications
CAS Number
[489427-17-0]
UNSPSC
12352209
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Cancer; Inflammation/Immunology
Smiles
C/C(C(NCCC(CCNC(CCCC(NCCCC[C@H]1C(N[C@H]2CSSC[C@H](C(N[C@H](C(N[C@@H](CSCC(N1)=O)C(NCCOCCOCCOCCNC(COCC(N)=O)=O)=O)=O)CC3=CC=CC=C3)=O)NC([C@@H](NC(CNC([C@@H](NC2=O)CCCNC(N)=N)=O)=O)CC(O)=O)=O)=O)=O)=O)CCNC(/C(C)=N/O)(C)C)(C)C)=N\O
Molecular Formula
C72H120N20O21S3
Molecular Weight
1698.04
References & Citations
[1]Gibbons, T., et al., (2024) . Safety, biodistribution and radiation dosimetry of the Arg-Gly-Asp peptide 99m Tc-maraciclatide in healthy volunteers. Nuclear medicine communications, 45 (4), 295-303
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
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