Neuropeptide AF1
Neuropeptide AF1 is a FMRFamide-like neuropeptide. Neuropeptide AF1 can be isolated from head extracts of the nematode Ascaris suum. Neuropeptide AF1 rapidly and reversibly abolishs slow membrane potential oscillations of identified ventral and dorsal inhibitory motoneurons and selectively reduces their input resistances. Neuropeptide AF1 inhibits locomotory movements in intact Ascaris[1].
Product Specifications
CAS Number
[130092-56-7]
UNSPSC
12352209
Target
Others
Related Pathways
Others
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H]([C@@H](C)CC)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(O)=O)NC([C@H](CC(N)=O)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O
Molecular Formula
C45H69N13O10
Molecular Weight
952.11
References & Citations
[1]Cowden C, et al. AF1, a sequenced bioactive neuropeptide isolated from the nematode Ascaris suum. Neuron. 1989 May;2 (5) :1465-73.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
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