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Neuropeptide AF1

Neuropeptide AF1 is a FMRFamide-like neuropeptide. Neuropeptide AF1 can be isolated from head extracts of the nematode Ascaris suum. Neuropeptide AF1 rapidly and reversibly abolishs slow membrane potential oscillations of identified ventral and dorsal inhibitory motoneurons and selectively reduces their input resistances. Neuropeptide AF1 inhibits locomotory movements in intact Ascaris[1].

Product Specifications

CAS Number

130092-56-7

UNSPSC

12352209

Target

Others

Related Pathways

Others

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(N)[C@H](CC1=CC=CC=C1)NC([C@H](CCCNC(N)=N)NC([C@H]([C@@H](C)CC)NC([C@H](CC2=CC=CC=C2)NC([C@H](CCC(O)=O)NC([C@H](CC(N)=O)NC([C@H](CCCCN)N)=O)=O)=O)=O)=O)=O

Molecular Formula

C45H69N13O10

Molecular Weight

952.11

References & Citations

[1]Cowden C, et al. AF1, a sequenced bioactive neuropeptide isolated from the nematode Ascaris suum. Neuron. 1989 May;2 (5) :1465-73.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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