ORG-2766

ORG-2766 is an adrenocorticotropic hormone ACTH 4-9 analog and neurotrophic peptide. ORG-2766 affects behavioral processes such as memory and attention in animals, improving symptoms in rats with experimental allergic neuritis. ORG-2766 has a neuroprotective effect[1][2].

Product Specifications

CAS Number

[50913-82-1]

UNSPSC

12352209

Target

Melanocortin Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Smiles

O=C(O)[C@H](CC1=CC=CC=C1)NC([C@@H](CCCCN)NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CNC=N3)NC([C@H](CCC(O)=O)NC([C@H](CCS(C)(=O)=O)N)=O)=O)=O)=O)=O

Molecular Formula

C40H55N9O11S

Molecular Weight

869.98

References & Citations

[1]Goldman H, et al. Cerebral blood flow after treatment with ORG-2766, a potent analog of ACTH 4--9. Pharmacol Biochem Behav. 1979 Jun;10 (6) :883-7.|[2]Duckers HJ, et al. The neurotrophic analogue of ACTH (4-9), Org 2766, protects against experimental allergic neuritis. Brain. 1993 Oct;116 (Pt 5) :1059-75.