ORG-2766
ORG-2766 is an adrenocorticotropic hormone ACTH 4-9 analog and neurotrophic peptide. ORG-2766 affects behavioral processes such as memory and attention in animals, improving symptoms in rats with experimental allergic neuritis. ORG-2766 has a neuroprotective effect[1][2].
Product Specifications
CAS Number
50913-82-1
UNSPSC
12352209
Target
Melanocortin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Smiles
O=C(O)[C@H](CC1=CC=CC=C1)NC([C@@H](CCCCN)NC([C@H](CC2=CC=CC=C2)NC([C@H](CC3=CNC=N3)NC([C@H](CCC(O)=O)NC([C@H](CCS(C)(=O)=O)N)=O)=O)=O)=O)=O
Molecular Formula
C40H55N9O11S
Molecular Weight
869.98
References & Citations
[1]Goldman H, et al. Cerebral blood flow after treatment with ORG-2766, a potent analog of ACTH 4--9. Pharmacol Biochem Behav. 1979 Jun;10 (6) :883-7.|[2]Duckers HJ, et al. The neurotrophic analogue of ACTH (4-9), Org 2766, protects against experimental allergic neuritis. Brain. 1993 Oct;116 (Pt 5) :1059-75.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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