Notch 1
Notch 1 (Notch homolog 1, translocation-associated) can encode a member of the NOTCH family of proteins. Members of this Type I transmembrane protein family share structural characteristics including an extracellular domain consisting of multiple epidermal growth factor-like (EGF) repeats, and an intracellular domain consisting of multiple different domain types[1].
Product Specifications
CAS Number
2408730-51-6
UNSPSC
12352209
Target
Notch
Related Pathways
Neuronal Signaling; Stem Cell/Wnt
Field of Research
Cancer; Cardiovascular Disease
Purity
95.39
Solubility
10 mM in DMSO
Smiles
OC(CC[C@@H](C(O)=O)NC([C@H](CS)NC([C@H]([C@@H](C)CC)NC([C@H](CS)NC([C@H](CCC(N)=O)NC([C@@H](NC([C@H](CCC(O)=O)NC(CNC([C@H]([C@@H](C)CC)NC([C@H](CCC(N)=O)NC([C@H](CC(O)=O)NC([C@H](CC(C)C)NC([C@@H](N)CS)=O)=O)=O)=O)=O)=O)=O)CC1=CC=CC=C1)=O)=O)=O)=O)=O)=O
Molecular Formula
C62H97N15O22S3
Molecular Weight
1500.72
References & Citations
[1]NOTCH1 notch receptor 1 [Homo sapiens (human) ] Gene ID: 4851, updated on 28-Oct-2019.|[2]toyanova T, et al. Activation of Notch1 synergizes with multiple pathways in promoting castration-resistant prostate cancer. Proc Natl Acad Sci U S A. 2016 Oct 18;113 (42) :E6457-E6466.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)
Scientific Category
Peptides
Clinical Information
No Development Reported
Available Sizes
Frequently Asked Questions
More Discoveries
Explore Other Products
Browse additional items from our catalog
orb3115557 100 µg
PYK2/PTK2B Rabbit Polyclonal Antibody (Fluoro594)
Sign In for Pricing
View Details 