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Cyclosporin E

Cyclosporin E (11-Demethylcyclosporin A) is a cyclic oligopeptide that can be isolated from fungi such as TTrichoderma polysporum and other imperfect fungi. Cyclosporin E belongs to the Cyclosporins family. Cyclosporin E can be used for studying the structure-activity relationships and molecular dynamic properties of cyclosporin compounds. As a structural control compound, Cyclosporin E holds significant research value in the fields of medicinal chemistry and biophysics[1][2].

Product Specifications

CAS Number

63798-73-2

Product Name Alternative

11-Demethylcyclosporin A

UNSPSC

12352209

Target

Biochemical Assay Reagents

Related Pathways

Others

Field of Research

Infection

Smiles

C/C=C/C[C@@H](C)[C@H]([C@]1([H])N(C([C@@H](NC([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)C)=O)C)=O)C)CC(C)C)=O)C)CC(C)C)=O)C(C)C)=O)C)O

Molecular Formula

C61H109N11O12

Molecular Weight

1188.58

References & Citations

[1]Traber R, et al. Neue Cyclopeptide aus Trichoderma polysporum (LINK EX PERS.) RIFAI: die Cyclosporine B, D und E [New cyclopeptides from Trichoderma polysporum (Link ex Pers.) Rifai: cyclosporins B, D and E (author's transl) ]. Helv Chim Acta. 1977;60 (5) :1568-78. German.|[2]Kobchikova P P, et al. Features of spatial structures of cyclosporins D, E and G revealed by NMR and MD simulations[J]. Journal of Molecular Liquids, 2021, 336: 116244.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Frequently Asked Questions

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