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Acetyl tetrapeptide-15

Acetyl tetrapeptide-15 is a synthetic peptide. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway. Acetyl tetrapeptide-15 is used in the cosmetics for sensitive skin[1].

Product Specifications

CAS Number

[928007-64-1]

UNSPSC

12352209

Target

Opioid Receptor

Related Pathways

GPCR/G Protein; Neuronal Signaling

Applications

Neuroscience-Neuromodulation

Field of Research

Neurological Disease

Purity

99.49

Solubility

DMSO : 100 mg/mL (ultrasonic)

Smiles

O=C([C@@H](NC([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC(C)=O)CC2=CC=C(C=C2)O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)N

Molecular Formula

C34H39N5O6

Molecular Weight

613.70

References & Citations

[1]Resende DISP, et al. Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. Pharmaceuticals (Basel) . 2021;14 (8) :702.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)

Scientific Category

Peptides

Clinical Information

No Development Reported

Isoform

μ Opioid Receptor/MOR

Available Sizes

Curated Selection

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