Acetyl tetrapeptide-15
Acetyl tetrapeptide-15 is a synthetic peptide. Acetyl tetrapeptide-15 is derived from endomorphin-2 (Tyr-Pro-Phe-Phe-NH2), a human μ-opioid agonist with selective anti-nociceptive effect. Acetyl tetrapeptide-15 reduces skin hyperreactivity producing inflammatory, chronic and neuropathic pain, by increasing the threshold of neuronal excitability in μ-opioid receptor via an endorphin-like pathway. Acetyl tetrapeptide-15 is used in the cosmetics for sensitive skin[1].
Product Specifications
CAS Number
[928007-64-1]
UNSPSC
12352209
Target
Opioid Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Neuroscience-Neuromodulation
Field of Research
Neurological Disease
Purity
99.49
Solubility
DMSO : 100 mg/mL (ultrasonic)
Smiles
O=C([C@@H](NC([C@@H](NC([C@H]1N(CCC1)C([C@@H](NC(C)=O)CC2=CC=C(C=C2)O)=O)=O)CC3=CC=CC=C3)=O)CC4=CC=CC=C4)N
Molecular Formula
C34H39N5O6
Molecular Weight
613.70
References & Citations
[1]Resende DISP, et al. Usage of Synthetic Peptides in Cosmetics for Sensitive Skin. Pharmaceuticals (Basel) . 2021;14 (8) :702.
Shipping Conditions
Blue Ice
Storage Conditions
-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture and light)
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
μ Opioid Receptor/MOR
Available Sizes
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