L803
L803 is a selective Somatostatin Receptor Subtype 4 (SST4) agonist. L803 inhibits L-type calcium channel currents (ICa) . L803 is promising for research of retinal ganglion cell (RGC) degenerative diseases (e.g., glaucoma) [1].
Product Specifications
CAS Number
348089-28-1
UNSPSC
12352209
Target
Somatostatin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Field of Research
Neurological Disease
Smiles
O=C([C@H]1N(CCC1)C([C@H](C)NC([C@H]2N(CCC2)C([C@H]3N(CCC3)C([C@H](C)NC([C@H](CCC(O)=O)NC([C@@H](N)CCCCN)=O)=O)=O)=O)=O)=O)N4[C@@H](CCC4)C(N[C@@H](CCC(N)=O)C(N[C@@H](COP(O)(O)=O)C(N5[C@@H](CCC5)C(O)=O)=O)=O)=O
Molecular Formula
C50H80N13O19P
Molecular Weight
1198.22
References & Citations
[1]Farrell SR, et al. Somatostatin receptor subtype 4 modulates L-type calcium channels via Gβγ and PKC signaling in rat retinal ganglion cells. Channels (Austin) . 2014;8 (6) :519-27.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
Phase 2
Isoform
SSTR4
Frequently Asked Questions
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