Ac-IETD-AFC (TFA)
Ac-IETD-AFC TFA is a synthetic fluorogenic substrate that can be used to specifically detect caspase-8 activity. INDO 1 pentasodium is imbued with the fluorophore AFC (7-amino-4-trifluoromethylcoumarin) . When caspase-8 recognizes and cleaves the amide bond following the IETD sequence in this substrate, AFC is released and emits fluorescence (Ex = ~400 nm; Em = ~505 nm) [1].
Product Specifications
UNSPSC
12352209
Target
Caspase
Related Pathways
Apoptosis
Field of Research
Others
Smiles
FC(C(O)=O)(F)F.FC(F)(C(C(C(O1)=C2)=CC=C2NC([C@H](CC(O)=O)NC([C@H]([C@H](O)C)NC([C@H](CCC(O)=O)NC([C@@H](NC(C)=O)[C@@H](C)CC)=O)=O)=O)=O)=CC1=O)F
Molecular Formula
C33H39F6N5O14
Molecular Weight
843.68
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Curated Selection
Explore Other Products
Discover premium biology products from our extensive collection of 20M+ items
MBS1437244-01 0.02 mg (E-Coli)
Recombinant Bacillus halodurans Lipoyl synthase (lipA)
Ask
View Details 
MBS1437244-02 0.02 mg (Yeast)
Recombinant Bacillus halodurans Lipoyl synthase (lipA)
Ask
View Details MBS1437244-03 0.1 mg (E-Coli)
Recombinant Bacillus halodurans Lipoyl synthase (lipA)
Ask
View Details