Miuraenamide A
Miuraenamide A is an antifungal and antitumor antibiotic. Miuraenamide A is also an actin filament stabilizer. Miuraenamide A stabilizes actin filaments. Miuraenamide A exhibits potent antifungal activity, particularly against the phytopathogenic oomycete Phytophthora capsici[1][2].
Product Specifications
CAS Number
905982-74-3
Product Name Alternative
SMH 27-4A
UNSPSC
12352209
Target
Antibiotic; Arp2/3 Complex; Fungal
Related Pathways
Anti-infection; Cytoskeleton
Field of Research
Cancer; Infection
Smiles
CO/C(C1=CC=CC=C1)=C(NC([C@@H](CC2=CC=C(O)C(Br)=C2)N(C)C([C@H](C)N3)=O)=O)\C(O[C@H](CC/C(C)=C\CCCC3=O)C)=O
Molecular Formula
C34H42BrN3O7
Molecular Weight
684.62
References & Citations
[1]Sumiya E, et al. Cell-morphology profiling of a natural product library identifies bisebromoamide and miuraenamide A as actin filament stabilizers. ACS Chem Biol. 2011 May 20;6 (5) :425-31. |[2]Liu Y, et al. Heterologous Biosynthesis of Myxobacterial Antibiotic Miuraenamide A. Molecules. 2023 Mar 20;28 (6) :2815.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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