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2-[O- (2-Azidoethyl) -D-serine]-cyclosporin A

2-[O- (2-Azidoethyl) -D-serine]-cyclosporin A (Compound 33) is a Cyclosporine derivative. 2-[O- (2-Azidoethyl) -D-serine]-cyclosporin A shows an IC50 of 0.11 μg/mL in the mixed lymphocyte reaction[1].

Product Specifications

CAS Number

[164028-89-1]

UNSPSC

12352209

Target

Drug Derivative

Related Pathways

Others

Field of Research

Inflammation/Immunology

Smiles

C/C=C/C[C@@H](C)[C@H]([C@]1([H])N(C([C@@H](N(C([C@@H](N(C([C@@H](N(C([C@H](NC([C@@H](NC([C@@H](N(C([C@@H](NC([C@@H](N(C(CN(C([C@@H](NC1=O)CC)=O)C)=O)C)CC(C)C)=O)C(C)C)=O)C)CC(C)C)=O)C)=O)COCCN=[N+]=[N-])=O)C)CC(C)C)=O)C)CC(C)C)=O)C)C(C)C)=O)C)O

Molecular Formula

C64H114N14O13

Molecular Weight

1287.68

References & Citations

[1]Eberle MK, et al. Preparation and in vitro activities of ethers of [D-serine]8-cyclosporin. J Med Chem. 1995 May 26;38 (11) :1853-64.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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