AWWNTEW

AWWNTEW is a ligand for target protein for PROTAC, targeting transcription factor FOXM1. AWWNTEW can be used for the synthesis of FPP29 (HY-P11228) [1].

Product Specifications

UNSPSC

12352209

Target

Ligands for Target Protein for PROTAC

Related Pathways

PROTAC

Applications

Cancer-programmed cell death

Field of Research

Cancer

Smiles

O=C(N[C@@H](CC1=CNC2=CC=CC=C12)C(N[C@@H](CC3=CNC4=CC=CC=C34)C(N[C@@H](CC(N)=O)C(N[C@@H]([C@H](O)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC5=CNC6=CC=CC=C56)C(O)=O)=O)=O)=O)=O)=O)[C@H](C)N

Molecular Formula

C49H57N11O12

Molecular Weight

992.04

References & Citations

[1]Jia S, et al. A novel designed fully peptide-based PROTAC, FPP29, demonstrates its potent cytotoxic effects to liver cancer HCCLM3 cells by targeting FOXM1. Bioorg Chem. 2025 Aug;163:108626.