APYIP
APYIP is a ligand for E3 ligase. APYIP recruits the VHL-E3 ubiquitin ligase. APYIP can be used for the synthesis of FPP29 (HY-P11228) [1].
Product Specifications
CAS Number
[882415-28-3]
UNSPSC
12352209
Target
Ligands for E3 Ligase
Related Pathways
PROTAC
Field of Research
Cancer
Smiles
O=C(N1[C@@H](CCC1)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H]([C@@H](C)CC)C(N3[C@@H](CCC3)C(O)=O)=O)=O)=O)[C@H](C)N
Molecular Formula
C28H41N5O7
Molecular Weight
559.65
References & Citations
[1]Jia S, et al. A novel designed fully peptide-based PROTAC, FPP29, demonstrates its potent cytotoxic effects to liver cancer HCCLM3 cells by targeting FOXM1. Bioorg Chem. 2025 Aug;163:108626.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
Von Hippel-Lindau (VHL)
Curated Selection
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