Ac2-26 (mouse)
Ac2-26 (mouse) is the N-terminal active peptide of Annexin A1 (AnxA1) . Ac2-26 (mouse) regulates the inflammatory response by modulating the formyl peptide receptor (FPR) signaling pathway. Ac2-26 (mouse) can promote the release of chemokines and inhibit the production of ROS. Ac2-26 (mouse) can be used for the research of inflammation, such as rheumatoid arthritis[1].
Product Specifications
CAS Number
164466-66-4
UNSPSC
12352209
Target
Formyl Peptide Receptor (FPR) ; Reactive Oxygen Species (ROS)
Related Pathways
GPCR/G Protein; Immunology/Inflammation; Metabolic Enzyme/Protease; NF-κB
Applications
COVID-19-immunoregulation
Field of Research
Inflammation/Immunology
Smiles
O=C(N[C@@H](CCSC)C(N[C@@H](C(C)C)C(N[C@@H](CO)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC(C)C)C(N[C@@H](CCCCN)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](CC2=CC=CC=C2)C(N[C@@H](CC(C)C)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC(N)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CCC(N)=O)C(N[C@@H](CCC(O)=O)C(N[C@@H](CC3=CC=C(C=C3)O)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](C(C)C)C(N[C@@H](CCCCN)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](C)NC(C)=O
Molecular Formula
C135H211N35O41S
Molecular Weight
3012.39
References & Citations
[1]Woloszynek JC, et al. Cathepsin G-regulated release of formyl peptide receptor agonists modulate neutrophil effector functions. J Biol Chem. 2012 Oct 5;287 (41) :34101-9.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Frequently Asked Questions
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