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Lipopeptide CPE4 (TFA)

Lipopeptide CPE4 TFA is a PEG-modified peptide E4 [ (EIAALEK) 4]. Lipopeptide CPE4 TFA is capable of coiled-coil formation when attached to liposomes. Lipopeptide CPE4 TFA triggers membrane fusion between liposomes and living cells with concomitant efficient cytosolic delivery of a variety of compounds such as fluorescent dyes Propidium Iodide (PI) and TO-PRO-3 iodide (HY-117070), and Doxorubicin (DOX) (HY-15142A). Lipopeptide CPE4 TFA can be used for drug delivery research[1].

Product Specifications

UNSPSC

12352209

Target

Liposome

Related Pathways

Metabolic Enzyme/Protease

Field of Research

Others

Purity

98.69

Smiles

CC(C)CCC[C@H]([C@@](CC[C@]1([C@@]2(CC=C(C3)[C@@]4(CC[C@@H]3NC(CCC(NCCOCCOCCOCCOCC(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N[C@H](C(N)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)CCCCN)=O)CCC(O)=O)=O)CC(C)C)=O)C)=O)C)=O)[C@H](CC)C)=O)CCC(O)=O)=O)=O)=O)C)[H])[H])([C@@](CC[C@@]24[H])1C)[H])C.OC(C(F)(F)F)=O.[x]

Molecular Formula

C177H303N35O51.xC2HF3O2

Molecular Weight

3737.50 (free base)

References & Citations

[1]Yang J, et al. Drug Delivery via Cell Membrane Fusion Using Lipopeptide Modified Liposomes. ACS Cent Sci. 2016 Sep 28;2 (9) :621-630.

Shipping Conditions

Blue Ice

Storage Conditions

-80°C, 2 years; -20°C, 1 year (Powder, sealed storage, away from moisture)

Scientific Category

Peptides

Clinical Information

No Development Reported

Available Sizes

Frequently Asked Questions

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