PSM-mec peptide

PSM-mec peptide is a peptide toxin belonging to the phenol-soluble modulin (PSM) superfamily. PSM-mec peptide is encoded by the psm-mec gene and associated with the methicillin resistance gene element (SCCmec) . PSM-mec peptide has pro-inflammatory, cytolytic functions and the role of regulating the structure of biofilms. PSM-mec peptide can be mainly used for the pathogenic mechanism and drug resistance research of canine pseudo-intermediate Staphylococcus (S. pseudintermedius) related infections and zoonotic diseases[1].

Product Specifications

CAS Number

[1708928-71-5]

UNSPSC

12352209

Target

Bacterial

Related Pathways

Anti-infection

Applications

COVID-19-immunoregulation

Field of Research

Infection

Purity

98.61

Solubility

DMSO : 20 mg/mL (ultrasonic)

Smiles

O=CN[C@H](CCSC)C(N[C@@H](CC(O)=O)C(N[C@@H](C(N[C@]([C@H](O)C)([H])C(NCC(N[C@@H](C(C)C)C(N[C@@]([C@@H](C)CC)(C(N[C@@]([C@H](O)C)(C(N[C@H](CO)C(N[C@@]([C@@H](C)CC)(C(N[C@@]([C@@H](C)CC)(C(N[C@@H](CC(O)=O)C(N[C@H](CC(C)C)C(N[C@]([C@H](CC)C)([H])C(N[C@H](CCCCN)C(N[C@@]([C@@H](C)O)(C(N[C@H](CS)C(N[C@@]([C@@H](C)CC)(C(N[C@H](CCC(N)=O)C(N[C@@H](C)C(N[C@@H](C(NCC=O)=O)CC1=CC=CC=C1)=O)=O)=O)[H])=O)=O)[H])=O)=O)=O)=O)=O)[H])=O)[H])=O)=O)[H])=O)[H])=O)=O)=O)=O)CC2=CC=CC=C2)=O)=O

Molecular Formula

C109H176N24O32S2

Molecular Weight

2414.86

References & Citations

[1]Cheung GYC, et al. Methicillin Resistance Elements in the Canine Pathogen Staphylococcus pseudintermedius and Their Association with the Peptide Toxin PSM-mec. Antibiotics (Basel) . 2024 Jan 28;13 (2) :130.