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MGCVQCKDKEA

MGCVQCKDKEA is an 11-residue membrane-anchoring motif derived from the Src kinase Fyn. MGCVQCKDKEA can promote the cell surface expression of TMC1/2 proteins. MGCVQCKDKEA can be used in the research of inner ear mechanical conduction channel-related diseases[1].

Product Specifications

CAS Number

[3084349-53-8]

UNSPSC

12352209

Target

Others

Related Pathways

Others

Field of Research

Others

Smiles

O=C(NCC(N[C@@H](CS)C(N[C@@H](C(C)C)C(N[C@@H](CCC(N)=O)C(N[C@@H](CS)C(N[C@@H](CCCCN)C(N[C@@H](CC(O)=O)C(N[C@@H](CCCCN)C(N[C@@H](CCC(O)=O)C(N[C@@H](C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N

Molecular Formula

C47H82N14O17S3

Molecular Weight

1211.43

References & Citations

[1]Chen Y, et al. Ectopic mouse TMC1 and TMC2 alone form mechanosensitive channels that are potently modulated by TMIE. Proc Natl Acad Sci U S A. 2025 Mar 4;122 (9) :e2403141122.

Shipping Conditions

Room temperature

Scientific Category

Peptides

Clinical Information

No Development Reported

Curated Selection

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