[Asp5,6, Me-Phe8] Substance P (5-11)
[Asp5,6, Me-Phe8] Substance P (5-11) is a tachykinin NK-3 receptor agonist. [Asp5,6, Me-Phe8] Substance P (5-11) reduces alcohol intake in genetically selected alcohol-preferring rats[1].
Product Specifications
UNSPSC
12352209
Target
Neurokinin Receptor
Related Pathways
GPCR/G Protein; Neuronal Signaling
Applications
Metabolism-protein/nucleotide metabolism
Field of Research
Metabolic Disease
Smiles
O=C(N[C@@H](CC(O)=O)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CC2=CC=C(C)C=C2)C(NCC(N[C@@H](CC(C)C)C(N[C@@H](CCSC)C(N)=O)=O)=O)=O)=O)=O)[C@H](CC(O)=O)N
Molecular Formula
C40H56N8O11S
Molecular Weight
856.98
References & Citations
[1]Ciccocioppo R, et al. Stimulation of tachykinin NK-3 receptors in the nucleus basalis magnocellularis reduces alcohol intake in rats. Peptides. 1997;18 (9) :1349-55.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
NK3R
Curated Selection
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