Cyclo (GRGDSPA)

Cyclo (GRGDSPA) is a cyclic RGD peptide targeting αvβ3 integrin. Cyclo (GRGDSPA) reduces the formation of colonies in mice injected with B16-FE7 melanoma cells. Cyclo (GRGDSPA) can be used for melanoma research[1][2].

Product Specifications

CAS Number

[128857-77-2]

UNSPSC

12352209

Target

Integrin

Related Pathways

Cytoskeleton

Field of Research

Cancer

Smiles

O=C1N2[C@@](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H]1CO)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)=O)C)=O)([H])CCC2

Molecular Formula

C25H40N10O10

Molecular Weight

640.65

References & Citations

[1]Hazenbiller O, et al. Reduction of pluripotent gene expression in murine embryonic stem cells exposed to mechanical loading or Cyclo RGD peptide. BMC Cell Biol. 2017 Nov 14;18 (1) :32.|[2]Kumagai H, et al. Effect of cyclic RGD peptide on cell adhesion and tumor metastasis. Biochem Biophys Res Commun. 1991 May 31;177 (1) :74-82.