Cyclo (GRGDSPA)
Cyclo (GRGDSPA) is a cyclic RGD peptide targeting αvβ3 integrin. Cyclo (GRGDSPA) reduces the formation of colonies in mice injected with B16-FE7 melanoma cells. Cyclo (GRGDSPA) can be used for melanoma research[1][2].
Product Specifications
CAS Number
128857-77-2
UNSPSC
12352209
Target
Integrin
Related Pathways
Cytoskeleton
Field of Research
Cancer
Smiles
O=C1N2[C@@](C(N[C@H](C(NCC(N[C@H](C(NCC(N[C@H](C(N[C@H]1CO)=O)CC(O)=O)=O)=O)CCCNC(N)=N)=O)=O)C)=O)([H])CCC2
Molecular Formula
C25H40N10O10
Molecular Weight
640.65
References & Citations
[1]Hazenbiller O, et al. Reduction of pluripotent gene expression in murine embryonic stem cells exposed to mechanical loading or Cyclo RGD peptide. BMC Cell Biol. 2017 Nov 14;18 (1) :32.|[2]Kumagai H, et al. Effect of cyclic RGD peptide on cell adhesion and tumor metastasis. Biochem Biophys Res Commun. 1991 May 31;177 (1) :74-82.
Shipping Conditions
Room temperature
Scientific Category
Peptides
Clinical Information
No Development Reported
Isoform
αvβ3
Frequently Asked Questions
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